Chemistry

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2007, No. 2



V.A. Ermokhin, P.P. Purygin, Y.P. Zarubin, P.N. Zolotarev

SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF N-(NITROPHENYL)-ADAMANTYL-1-CARBOXAMIDES AND ADAMANTANE DERIVATIVES OF N-METHYLPYRIDINE IODIDE

In the paper the antibacterial activity of synthesized compound of adamantane. It is found that compound with adamantoyl radical in para have the highest activity level.
Aromatic and heterocyclic derivatives of adamantane are synthesized and their antibacterial activity is investigated. It is established that the compounds having adamantane substituent in para-position in relation to nitrogroup and endocyclic nitrogen have the highest activity level.


A.V. Voronin, I.F. Shatalaev, T.V. Voevodina, P.P. Purygin

GAS-CHROMATOGRAPHY-MASS-SPECTROMETRY IDENTIFICATION OF MORPHINE AND CODEINE IN FORENSIC CHEMICAL ANALYSIS

Analytical characteristics of gas-chromatography-mass-spectrometry identi- fication procedure of morphine and codeine in blood are considered. The detection limit for morphine in blood were 2400,0 ng/mL under total ion current conditions and 100,0 ng/mL under selected ion monitoring conditions; for codeine — 200,0 and 40,0 ng/mL respectively. The detection limit of morphine and codeine as acetic and trifluoroacetic derivatives in forensic chemical analysis is lower.


P.P. Purigin, N.N. Zhelonkin, O.N. Pavlova, S.V. Pervushkin, V.A. Khurkin, U.L. Gerasimov, T.Y. Boronets

ANALYSIS OF TOXICITY AND ANTIOXIDANT ACTIVITY BIOMASS AND OFFICINAL CONFORMATION OF ALGA SPIRULINA PLATENSIS

To study properties biomass and spray of alga spirulina platensis we pay special attention to toxicity and antioxidant activity. Investigation of the toxicity conduct on the water flea Research of antioxidant activity found on inhibition oxidation of adrenalin with antioxidant contain in alga spirulina platensis. The result of our work agree with accepted theory.