Chemistry

2004, No. 4

V.V. Vishnyakov, P.P. Purygin, I.A. Potapova, S.V. Pankov

SYNTHESIS OF 5-SUBSTITUTION TETRAZOLES FROM N-CYANDERIVATIVE NITROGEN CONTAINING HETEROCYCLES

5-heteryltetrazoles with a good yield interaction N-cyanderivants of aromatic nitrogen compound heterocycles with sodium azide in environment of aqueous acetonitrile are synthesized.

V.А. Ermokhin, P.P. Purygin, N.A. Klenova

SYNTHESIS AND HAEMOLYTIC ACTIVITY OF 1-ADAMANTOYL DERIVATIVES OF HETEROCYCLIC AMINES AND ANILINES

1-А damantoylamides and 1-adamantylmethyl-4-bromoaniline are synthesized and tested on haemolytic activity. Some of tested 1-adamantoyl-amides show realistically smaller damaging action in comparing with amantadine and are perspective for experimental analysis of their biological activity.